The modular system for laboratory-scale cell cultivation
The CELLROLL and CELLSPIN systems are based on a modular assembly concept that allows you to configure and combine
the two instruments according to your needs. Using only one control unit it is possible to operate two CELLROLL drive units or
two CELLSPIN stirring platforms or a combination of one instrument each. The control unit automatically recognises the type of
instrument connected and allows you to independently store ten different cell cultivation programs for each unit.
Designed for a “lifelong” use in CO2-incubators
The control unit contains all sensitive electronic parts and con-nects via cable to the drive unit, therefore it can be kept outside of the incubator and the electronics are not damaged by the incubator‘s humidity. The materials used for the CELLROLL drive unit and the CELLSPIN stirring platform are non-corroding and the motor housings are sealed tightly – all this makes sure that a reliable and long-lived system will keep your cells always “on the move”!
For quality conscious cell culture laboratories
Because quality assurance is an integral part of a cell-based manufacturing process, the CELLROLL and CELLSPIN systems offer the means to efficiently monitor and document cell cultivation. Both instruments can be connected to a printer or a PC to log cultivation parameters at specified time intervals and to record all saved culture protocols. Also an interruption of the cultivation process – either due to a power failure or to an accidental disconnection of the control unit – doesn‘t go unnoticed: the control unit triggers a beeping alarm and generates an error message.
CELLSPIN:-
Adaptable to your specific needs
On each CELLSPIN stirring platform up to four spinner flasks can be employed independently of their size. The CELLSPIN spinner flasks are available in four different sizes – 100 ml, 250 ml, 500 ml and 1000 ml – to match individual needs of cultivation scale. Using the conversion kit for impeller-type flasks, the individual stirring positions of the stirring unit can easily be adapted for use with other spinner flasks.
Optimised for cell cultivation
An optimised culture protocol is a key factor for successful cultivation of cells. CELLSPIN allows you to precisely set para-
meters such as stirring speed, pause intervals and pendular angels for inversion of the rotation direction. The speed ranges from 5 to 75 rpm and can be adjusted in steps of 2.5 rpm (5-40 rpm) or in steps of 5 rpm (40-75 rpm). The CELLSPIN spinner flasks are designed to provide a high surface to volume ratio ensuring improved oxygenation over standard designs. The unique stirring mechanism of the CELLSPIN spinner flasks relies on two glass pendula which guarantee low shear forces while maintaining optimum mixing. As most cells are very sensitive to overheating, the stirring platform design prevents any release and transfer of heat to the cell suspension. Owing to these specific measures aimed at gentle cell cultivation, high yield expression from even the most sensitive cell lines is possible.
CELLROLL:-
Optimised for cell cultivation Successful growth of cells in roller bottles often relies on opti-mal rolling speed and therefore the CELLROLL allows fine-tun-ing of the rotation speed. The standard drive unit operates in a speed range from 0.1 to 2 rpm and is adjustable in steps of 0.1 rpm. The faster drive unit rotates the roller bottles with 2 to 6 rpm (adjustable in steps of 0.5 rpm).
To avoid unnecessary shear stress, all the rolls of the instru-ment are turning on high-quality ball-bearings free of vibrations and are driven by a stepper motor which guarantees a com-pletely smooth rolling start and stop.
Adaptable to specific needs
The modular design of the CELLROLL allows scale-up of bot-tle capacity from 4 to 16 roller bottles. By using two drive units up to 32 roller bottles can be operated using one control unit only. The customised configuration of CELLROLL increases flexibility and efficiency of the lab.